Cardiovascular toxicity of illicit anabolic-androgenic steroid use
Long-term AAS use was associated with myocardial dysfunction and coronary atherosclerosis.
Observational; exposure self-selected.
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Anabolic-androgenic steroid
methandienone
Dianabol is an oral steroid used for bigger muscles, more strength and a fuller look. Some of the increase in size and scale weight is water. Unlike the low-water finishing drugs, estrogen-related bloating can be a noticeable part of its effect. Main downsides are breast changes, higher blood pressure, worse cholesterol and liver injury.
Older human studies document anabolic/clinical effects and unfavorable lipid/liver changes. Evidence is dated and does not establish safe nonmedical use.
Liver injury, fluid retention, hypertension, gynecomastia, HDL/LDL deterioration and gonadal suppression.
AST/ALT/bilirubin; HDL/LDL/triglycerides; blood pressure; edema; reproductive hormones.
Not currently approved in the United States; not approved for bodybuilding.
Other aliases: methandienone · methandrostenolone
Long-term AAS use was associated with myocardial dysfunction and coronary atherosclerosis.
Observational; exposure self-selected.
Original source ↗Documented adverse biochemical changes.
Old methods and limited sample.
Original source ↗Historical medical efficacy/safety data.
Not relevant to physique use.
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