Tesamorelin is used to reduce deep belly fat in adults with HIV-related lipodystrophy. It boosts growth-hormone release rather than supplying growth hormone directly. It targets that specific fat problem without much change in total weight, so it is not a general cutting drug. Swelling, joint pain and higher blood sugar are the main drawbacks.
Ratings
Muscle gain2/10
Fullness4/10
Bloat4/10
Dryness4/10
Hair loss1/10
Mental sides2/10
Physical sides6/10
Overall7/10
Practical details
Medical dose
1.28 mg once daily
Treatment duration
Ongoing therapy with reassessment of abdominal-fat response, IGF-1 and glucose
Route / formulation
Subcutaneous injection; Egrifta WR formulation only
Egrifta WR for excess abdominal fat in adults with HIV-associated lipodystrophy. WR and SV formulations have different doses and are not interchangeable; this amount does not describe generic research tesamorelin.
Known for
Deep abdominal fat in HIV lipodystrophy · Growth-hormone release · Little change in total weight
Controlled trials and official labeling support its narrow HIV-lipodystrophy indication, not general fat loss, muscle gain or anti-aging use.
Interactions & monitoring
Increased IGF-1, fluid retention, joint symptoms, glucose intolerance or diabetes, injection reactions and contraindications related to malignancy and pregnancy; long-term cardiovascular safety is not established.
IGF-1, glucose status, edema and joint symptoms, injection sites and malignancy-related considerations under specialist care.
Medical context
Approved to reduce excess abdominal fat in adults with HIV-associated lipodystrophy. It is not indicated for general weight loss or bodybuilding.